hy 151427 Search Results


94
MedChemExpress tgf β1
Effects of LG2 on cell viability in A549 and MRC5 cells. (A,B) Cytotoxicity of LG2 in A549 and MRC5 cells following 48-h treatment with various doses. (C,D) Impact of LG2 on cell viability in <t>TGF-β1–induced</t> A549 and MRC5 cells post 48-h treatment (n = 3).* p < 0.05, ** p < 0.005, *** p < 0.001, compared to the Ctrl group (TGF-β1, 5 ng/mL).
Tgf β1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Effects of LG2 on cell viability in A549 and MRC5 cells. (A,B) Cytotoxicity of LG2 in A549 and MRC5 cells following 48-h treatment with various doses. (C,D) Impact of LG2 on cell viability in TGF-β1–induced A549 and MRC5 cells post 48-h treatment (n = 3).* p < 0.05, ** p < 0.005, *** p < 0.001, compared to the Ctrl group (TGF-β1, 5 ng/mL).

Journal: Frontiers in Pharmacology

Article Title: Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition

doi: 10.3389/fphar.2024.1437231

Figure Lengend Snippet: Effects of LG2 on cell viability in A549 and MRC5 cells. (A,B) Cytotoxicity of LG2 in A549 and MRC5 cells following 48-h treatment with various doses. (C,D) Impact of LG2 on cell viability in TGF-β1–induced A549 and MRC5 cells post 48-h treatment (n = 3).* p < 0.05, ** p < 0.005, *** p < 0.001, compared to the Ctrl group (TGF-β1, 5 ng/mL).

Article Snippet: Bleomycin (BLM, HY17565), pirfenidone (HYB0673), TGF-β1 (HY-151427) and Etanercept (HY-108847) were acquired from MedChemExpress, Princeton, United States.

Techniques:

Inhibition of TGF-β1–induced migration in A549 cells by LG2. (A) Effects of LG2 on enhanced migration ability of A549 cells induced by TGF-β1, determined via a transwell migration assay. (B) Quantitative analysis using ImageJ software. (C) IF image showing α-SMA distribution. (D) Quantitative analysis of α-SMA expression. (E) IF image showing Collagen I distribution. (F) Quantitative analysis of Collagen I expression (scale bar = 50 μm) (n = 3). * p < 0.05, ** p < 0.005, *** p < 0.001, compared to the Model group. # p < 0.05, ## p < 0.005, ### p < 0.001, compared to the Ctrl group.

Journal: Frontiers in Pharmacology

Article Title: Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition

doi: 10.3389/fphar.2024.1437231

Figure Lengend Snippet: Inhibition of TGF-β1–induced migration in A549 cells by LG2. (A) Effects of LG2 on enhanced migration ability of A549 cells induced by TGF-β1, determined via a transwell migration assay. (B) Quantitative analysis using ImageJ software. (C) IF image showing α-SMA distribution. (D) Quantitative analysis of α-SMA expression. (E) IF image showing Collagen I distribution. (F) Quantitative analysis of Collagen I expression (scale bar = 50 μm) (n = 3). * p < 0.05, ** p < 0.005, *** p < 0.001, compared to the Model group. # p < 0.05, ## p < 0.005, ### p < 0.001, compared to the Ctrl group.

Article Snippet: Bleomycin (BLM, HY17565), pirfenidone (HYB0673), TGF-β1 (HY-151427) and Etanercept (HY-108847) were acquired from MedChemExpress, Princeton, United States.

Techniques: Inhibition, Migration, Transwell Migration Assay, Software, Expressing